Little discovery in the laboratory: a new route for 144222-22-0

Compounds in my other articles are similar to this one(1-Boc-4-(Aminomethyl)piperidine)Name: 1-Boc-4-(Aminomethyl)piperidine, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804M Kinase, published in 2020-04-09, which mentions a compound: 144222-22-0, Name is 1-Boc-4-(Aminomethyl)piperidine, Molecular C11H22N2O2, Name: 1-Boc-4-(Aminomethyl)piperidine.

A combination of focused library and virtual screening, hit expansion, and rational design has resulted in the development of a series of inhibitors of RETV804M kinase, the anticipated drug-resistant mutant of RET kinase. These agents do not inhibit the wild type (wt) isoforms of RET or KDR and therefore offer a potential adjunct to RET inhibitors currently undergoing clin. evaluation.

Compounds in my other articles are similar to this one(1-Boc-4-(Aminomethyl)piperidine)Name: 1-Boc-4-(Aminomethyl)piperidine, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem