Li, Guiying et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2011 | CAS: 58333-75-8

4-(2-Methoxyphenyl)piperidine (cas: 58333-75-8) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair conformations: one with the N–H bond in an axial position, and the other in an equatorial position.HPLC of Formula: 58333-75-8

Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperidin-3-yl-cyclopropanecarboxamide derivatives as novel melatonin receptor ligands was written by Li, Guiying;Zhou, Hao;Jiang, Yu;Keim, Holger;Topiol, Sidney W.;Poda, Suresh B.;Ren, Yong;Chandrasena, Gamini;Doller, Dario. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2011.HPLC of Formula: 58333-75-8 This article mentions the following:

Two series of 4-aryl-1-cyclopropanecarbonylpiperidines (I) and 1-arylpiperidin-3-ylcyclopropanecarboxamides (II), exhibiting diverse functionality at rat MT1 and MT2 receptors, are reported. I and (S)-II [aryl = 3-MeOC6H4] (MT1/MT2 agonist) have human microsomal intrinsic clearance comparable to ramelteon. In the experiment, the researchers used many compounds, for example, 4-(2-Methoxyphenyl)piperidine (cas: 58333-75-8HPLC of Formula: 58333-75-8).

4-(2-Methoxyphenyl)piperidine (cas: 58333-75-8) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair conformations: one with the N–H bond in an axial position, and the other in an equatorial position.HPLC of Formula: 58333-75-8

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem