Let`s talk about compound :1,4-Dioxa-8-azaspiro[4.5]decane

SDS of cas: 177-11-7. About 1,4-Dioxa-8-azaspiro[4.5]decane, If you have any questions, you can contact Chen, YH; Lv, WW; Ba, D; Wen, S; Cheng, GL or concate me.

I found the field of Chemistry very interesting. Saw the article Palladium-Catalyzed Chemoselective Synthesis of 2-Aminocinnamyl Esters via Sequential Amination and Olefination of Aryl Iodides published in 2020. SDS of cas: 177-11-7, Reprint Addresses Cheng, GL (corresponding author), Huaqiao Univ, Coll Mat Sci & Engn, Xiamen 361021, Peoples R China.. The CAS is 177-11-7. Through research, I have a further understanding and discovery of 1,4-Dioxa-8-azaspiro[4.5]decane

We report a highly chemoselective palladium-catalyzed Catellani-type amination of aryl iodides terminated by the Heck reaction using allylic esters as terminating reagents. 2-Aminocinnamyl esters were formed exclusively via beta-H elimination rather than beta-OAc elimination without the assistance of a silver salt. This protocol represents a useful extension of Catellani-type transformations.

SDS of cas: 177-11-7. About 1,4-Dioxa-8-azaspiro[4.5]decane, If you have any questions, you can contact Chen, YH; Lv, WW; Ba, D; Wen, S; Cheng, GL or concate me.

Reference：
Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem