Chiral amino-amides as solution phase and immobilized ligands for the catalytic asymmetric alkylation of aromatic aldehydes was written by Lesma, Giordano;Danieli, Bruno;Passarella, Daniele;Sacchetti, Alessandro;Silvani, Alessandra. And the article was included in Letters in Organic Chemistry in 2006.Formula: C12H15NO3S This article mentions the following:
Novel chiral amino-amide 9-keto-bispidines are investigated as ligands in the addition reaction of diethylzinc to aromatic aldehydes. The ligands are easily obtained by a single-step procedure starting from com. available products. Selected ligands were also supported onto different insoluble resins in order to test their activity as heterogeneous catalysts. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Formula: C12H15NO3S).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Formula: C12H15NO3S
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem