Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy [Erratum to document cited in CA161:346388] was written by Lee, Kin Sing Stephen;Liu, Jun-Yan;Wagner, Karen M.;Pakhomova, Svetlana;Dong, Hua;Morisseau, Christophe;Fu, Samuel H.;Yang, Jun;Wang, Peng;Ulu, Arzu;Mate, Christina A.;Nguyen, Long V.;Hwang, Sung Hee;Edin, Matthew L.;Mara, Alexandria A.;Wulff, Heike;Newcomer, Marcia E.;Zeldin, Darryl C.;Hammock, Bruce D.. And the article was included in Journal of Medicinal Chemistry in 2018.Computed Properties of C16H20F3N3O3 The following contents are mentioned in the article:
In the legend within Figure S11, the yellowish green line with solid triangle should be inhibitor 21 instead of inhibitor 19, while green line with open triangle should be inhibitor 19 instead of inhibitor 21. The corresponding structures should be swapped too. The correct Figure S11 is provided here. This study involved multiple reactions and reactants, such as 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea (cas: 1222780-33-7Computed Properties of C16H20F3N3O3).
1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea (cas: 1222780-33-7) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Computed Properties of C16H20F3N3O3
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem