Direct Construction of Quaternary Carbons from Tertiary Alcohols via Photoredox-Catalyzed Fragmentation of tert-Alkyl N-Phthalimidoyl Oxalates was written by Lackner, Gregory L.;Quasdorf, Kyle W.;Overman, Larry E.. And the article was included in Journal of the American Chemical Society in 2013.Recommanded Product: 1-Boc-4-Hydroxy-4-methylpiperidine This article mentions the following:
A convenient method for the direct construction of quaternary carbons from tertiary alcs. by visible-light photoredox coupling of tert-alkyl N-phthalimidoyl oxalate intermediates with electron-deficient alkenes is reported. In the experiment, the researchers used many compounds, for example, 1-Boc-4-Hydroxy-4-methylpiperidine (cas: 406235-30-1Recommanded Product: 1-Boc-4-Hydroxy-4-methylpiperidine).
1-Boc-4-Hydroxy-4-methylpiperidine (cas: 406235-30-1) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Recommanded Product: 1-Boc-4-Hydroxy-4-methylpiperidine
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem