Synthesis of piperazine and its salts was written by Krishnan, V.;Muthkumaran, A.;Udupa, H. V. K.. And the article was included in Indian Journal of Technology in 1975.Electric Literature of C4H12Cl2N2 This article mentions the following:
Dioxopiperazine was prepared from glycine and then reduced electrolytically at low temperature to piperazine at Pb and Cu amalgamated electrodes. Piperazine dihydrochloride and citrate were prepared Zn dust distillation of piperazine gave pyrazine. In the experiment, the researchers used many compounds, for example, Piperazine Dihydrochloride (cas: 142-64-3Electric Literature of C4H12Cl2N2).
Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine is a fairly basic compound and is an amine solvent. Piperazines are very broad chemical group, covering a wide range of drugs from antidepressants to antihistamines. The connecting property of all these chemicals is the presence of a piperazine functional group.Electric Literature of C4H12Cl2N2
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics