Jost, Micha et al. published their research in Chemistry & Biodiversity in 2007 | CAS: 86069-86-5

(S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid (cas: 86069-86-5) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair conformations: one with the N–H bond in an axial position, and the other in an equatorial position.Recommanded Product: (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid

Synthesis and structural and biological studies of efrapeptin C analogues was written by Jost, Micha;Weigelt, Sven;Huber, Thomas;Majer, Zsuzsanna;Greie, Joerg-Christian;Altendorf, Karlheinz;Sewald, Norbert. And the article was included in Chemistry & Biodiversity in 2007.Recommanded Product: (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid The following contents are mentioned in the article:

A series of analogs of efrapeptin C, with variations in the central tripeptide epitope Leu-β-Ala-Gly (positions 6-8), were prepared by a combination of solid- and solution-phase peptide syntheses. The conformations of the modified compounds (Xaa6-Xaa7-Xaa8 = Leu-Gly-βAla, β-Ala-Leu-Gly, β3HLeu-Gly-Gly, Leu-β3-HPhe-Gly, Leu-Aib-Gly) were investigated by circular-dichroism (CD) spectroscopy to differentiate between 310– and α-helical secondary structures. The inhibitory activities of the new compounds towards F1-ATPase from E. coli were determined Threee modified congeners were less active by one order of magnitude compared to efrapeptin C (Ki 10 μM), and one was completely inactive. Our experiments demonstrate that the flexible, central tripeptide epitope, comprising positions 6-8 in efrapeptin C, is crucial for mol. recognition, even slight sequence modifications being hardly tolerated. This study involved multiple reactions and reactants, such as (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid (cas: 86069-86-5Recommanded Product: (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid).

(S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid (cas: 86069-86-5) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair conformations: one with the N–H bond in an axial position, and the other in an equatorial position.Recommanded Product: (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem