Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. Safety of 2,2,6,6-Tetramethyl-4-piperidinol.
Huang, Zhuofan;Lin, Qintie;Cai, Nan;Weng, Qingsong;Xu, Jingwei;Gan, Shuchai;Chen, Chao;Zhong, Quanfa;Fu, Hengyi;Xia, Yuejie;Guo, Pengran research published 《 Coexistence of free radical and nonradical mechanisms for triclosan degradation by CuO/HNTs》, the research content is summarized as follows. In this study, CuO/HNTs were applied to activate persulfate (PS) to firstly degrade and mineralize TCS. The morphol., crystal structure, sp. surface and surface composition were characterized by SEM, TEM, BET, XRD and XPS. The exptl. parameters were optimized with 0.2 g/L CuO/HNTs and 2 mM PS. TCS was totally removed in 180 min under optimized conditions. The mechanism study using the quenching reaction, EPR, XPS and electrochem. demonstrated that even radical reactions (·OH and O·-2) pathway existed; the nonradical mechanism (1O2 and surface electron transport) was dominant to the efficient TCS degradation Using FT-ICR MS, the degradation intermediates were identified, and transformation pathways were proposed. The degradation intermediate studies indicated that TCS began to break from the aromatic ring containing monochlorine, and the Cl functional group was gradually substituted. CO2 and H2O were generated with breaking of ether bonds. The toxicity of the solution was also evaluated by the survival rate of the luminescent bacteria, and the toxicity of the solution decreased overall. A stability study showed that CuO/HNTs retained good crystal structure and degradation efficiency even after 5 cycles.
Safety of 2,2,6,6-Tetramethyl-4-piperidinol, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem