On September 8, 2017, Himmelsbach, Frank; Blum, Andreas; Peters, Stefan published a patent.HPLC of Formula: 1251006-64-0 The title of the patent was Preparation of 4-cyanobenzyl carbamimidoylcarbamate derivatives as AOC3 inhibitors. And the patent contained the following:
The invention relates to new benzonitrile derivatives I [R1 = H or halo; R2 = H or halo;R3 = H or halo (with the proviso that not more than one of R1-R3 is halo); A = II-IV, etc. (R4 = pyrrolidinyl, piperidinyl, piperazinyl; a CH2 group of the pyrrolidinyl, oxazolidinyl, piperidinyl or piperazinyl group of R4 is optionally replaced with a C(O) group)] or a pharmaceutically acceptable salt thereof, to their medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them. Over ninety compounds I were prepared E.g., a multi-step synthesis of compound V, starting from 4-bromo-2,5-difluoro-benzonitrile and 4-(piperazinyl)benzonitrile, was described. Exemplified compounds I were tested in the AOC3 assay (IC50 values given). The experimental process involved the reaction of tert-Butyl 3-(piperidin-4-yl)azetidine-1-carboxylate(cas: 1251006-64-0).HPLC of Formula: 1251006-64-0
The Article related to cyanobenzyl carbamimidoylcarbamate aoc3 inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.HPLC of Formula: 1251006-64-0
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem