On September 8, 2017, Himmelsbach, Frank; Blum, Andreas; Peters, Stefan published a patent.Recommanded Product: tert-Butyl 3-(piperidin-4-yl)azetidine-1-carboxylate The title of the patent was Preparation of pyridinylmethyl carbamimidoylcarbamate derivatives as AOC3 inhibitors. And the patent contained the following:
The invention relates to new heteroaryl derivatives I [X1 = N and CH; X2 = N and CF (with the proviso that at least one of X1 and X2 is N); A = II-IV (R4 = (un)substituted azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, etc.)] or a pharmaceutically acceptable salt thereof, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them. Over one-hundred compounds I were prepared General procedures for preparation of compounds I were provided. For example, compound I was prepared, starting from (2,3-difluoro-4-pyridyl)methanol and 3-phenylazetidine. Exemplified compounds I were tested for their pharmacol. activity in the AOC3 assay (IC50 values were given). The experimental process involved the reaction of tert-Butyl 3-(piperidin-4-yl)azetidine-1-carboxylate(cas: 1251006-64-0).Recommanded Product: tert-Butyl 3-(piperidin-4-yl)azetidine-1-carboxylate
The Article related to pyridinylmethyl carbamimidoylcarbamate preparation aoc3 vascular adhesion protein 1 inhibitor, heteroaryl carbamimidoylcarbamate preparation aoc3 vascular adhesion protein 1 inhibitor and other aspects.Recommanded Product: tert-Butyl 3-(piperidin-4-yl)azetidine-1-carboxylate
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem