Hammouda, M. et al. published their research in Pharmazie in 1988 | CAS: 142-64-3

Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Synthetic Route of C4H12Cl2N2

Synthesis and some reactions of 2-(3-aminopropionyl)-1,3-indandiones was written by Hammouda, M.;Hamama, W. S.;Kandeel, E. M.;Afsah, E. M.. And the article was included in Pharmazie in 1988.Synthetic Route of C4H12Cl2N2 This article mentions the following:

The title compounds I (R2N = 1,4-piperazinediyl, Me2N, morpholino) were prepared by Mannich reaction of 2-acetyl-1,3-indandione (II) with R2NH and CH2O. Reactions of I with PhNH2, glycine, piperazine, PhNHNH2, and HONH2 were investigated. Thus, I (R2N = morpholino) and PhNHNH2 gave the indenopyrazole III. II and HSCH2CO2H gave the thiazolidine IV. In the experiment, the researchers used many compounds, for example, Piperazine Dihydrochloride (cas: 142-64-3Synthetic Route of C4H12Cl2N2).

Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Synthetic Route of C4H12Cl2N2

Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics