Hammer, C. F. published the artcileReactions of β-substituted amines. II. Nucleophilic displacement reactions on 3-chloro-1-ethylpiperidine, Quality Control of 13444-24-1, the publication is Tetrahedron (1972), 28(2), 239-53, database is CAplus.
Synthetic, kinetic, and optical activity studies established that 3-chloro-1-ethylpiperidine undergoes nucleophilic displacement reactions in solution by a 2-step, neighboring group participation mechanism. N displaces chloride internally, to give an ambident bicyclic aziridinium ion, which then reacts with nucleophiles to give pyrrolidine and piperidine isomers. The aziridinium ion, 1-ethyl-1-azoniabicyclo[3.1.0]hexane perchlorate, was synthesized sep.
Tetrahedron published new progress about 13444-24-1. 13444-24-1 belongs to piperidines, auxiliary class Piperidine,Alcohol, name is 1-Ethylpiperidin-3-ol, and the molecular formula is C7H15NO, Quality Control of 13444-24-1.
Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem