Guo, Junkai’s team published research in Nature Communications in 2022-12-31 | CAS: 887425-47-0

Nature Communications published new progress about Alkyl azides Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 887425-47-0 belongs to class piperidines, name is 1-(5-Bromopyrimidin-2-yl)piperidin-4-ol, and the molecular formula is C9H12BrN3O, Synthetic Route of 887425-47-0.

Guo, Junkai published the artcileSulfoxFluor-enabled deoxyazidation of alcohols with NaN3, Synthetic Route of 887425-47-0, the main research area is alc sulfoxfluor sodiumazide deoxyazidation; alkyl azide preparation.

Direct deoxyazidation of alcs. with NaN3 is a straightforward method for the synthesis of widely used alkyl azides in organic chem. A general and practical method for the preparation of alkyl azides from alcs. using NaN3 was developed. N-tosyl-4-chlorobenzenesulfonimidoyl fluoride (SulfoxFluor) played an important role in this deoxyazidation process, which converted a broad range of alcs. into alkyl azides at room temperature The power of this deoxyazidation protocol was demonstrated by successful late-stage deoxyazidation of natural products and pharmaceutically relevant mols.

Nature Communications published new progress about Alkyl azides Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 887425-47-0 belongs to class piperidines, name is 1-(5-Bromopyrimidin-2-yl)piperidin-4-ol, and the molecular formula is C9H12BrN3O, Synthetic Route of 887425-47-0.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem