Gao, Chang et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2016 | CAS: 406235-30-1

1-Boc-4-Hydroxy-4-methylpiperidine (cas: 406235-30-1) belongs to piperidine derivatives.Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Application of 406235-30-1

Visible-light photoredox synthesis of internal alkynes containing quaternary carbons was written by Gao, Chang;Li, Jingjing;Yu, Jipan;Yang, Haijun;Fu, Hua. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2016.Application of 406235-30-1 This article mentions the following:

A novel and efficient visible-light photoredox method for the synthesis of internal alkynes RCCAr (R = tert-Bu, 1-methylcyclohexyl, 1-methylcycloheptyl, etc.; Ar = C6H5, thiophen-2-yl, naphthalen-1-yl, etc.) containing quaternary carbons has been developed via coupling reactions of N-phthalimidoyl oxalates of tert-alcs. I with 1-(2-(arylsulfonyl)ethynyl)benzenes ArCCS(O)2C6H5. The reactions proceeded well at room temperature with good functional group tolerability. In the experiment, the researchers used many compounds, for example, 1-Boc-4-Hydroxy-4-methylpiperidine (cas: 406235-30-1Application of 406235-30-1).

1-Boc-4-Hydroxy-4-methylpiperidine (cas: 406235-30-1) belongs to piperidine derivatives.Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Application of 406235-30-1

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem