Final Thoughts on Chemistry for 10314-98-4

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Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Quality Control of: N-Cbz-4-Piperidinecarboxylic acid, Which mentioned a new discovery about 10314-98-4

(2S)-2-(3-Chlorophenyl)-1-[N-(methyl)-N-(phenylsulfonyl)amino]-4-[spiro (2,3-dihydrobenzthiophene-3,4?-piperidin-1?-yl)]butane S-oxide (1b) has been identified as a potent CCR5 antagonist having an IC50 = 10 nM. Herein, structure-activity relationship studies of non-spiro piperidines are described, which led to the discovery of 4-(N-(alkyl)-N-(benzyloxycarbonyl)amino)piperidine derivatives (3-5) as potent CCR5 antagonists.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 10314-98-4, help many people in the next few years.Quality Control of: N-Cbz-4-Piperidinecarboxylic acid

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21579N – PubChem