Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， category: piperidines, Which mentioned a new discovery about 2213-43-6
The structure-activity relationship (SAR) study of two chemotypes identified as inhibitors of the human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD, 15-PGDH) was conducted. Top compounds from both series displayed potent inhibition (IC50 <50 nM), demonstrate excellent selectivity towards HPGD and potently induce PGE 2 production in A549 lung cancer and LNCaP prostate cancer cells. I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 2213-43-6, help many people in the next few years.category: piperidines
Reference：
Piperidine – Wikipedia,
Piperidine | C5H654N – PubChem