Extracurricular laboratory:new discovery of 301673-14-3

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Reference of 301673-14-3, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.301673-14-3, Name is tert-Butyl 4-iodopiperidine-1-carboxylate, molecular formula is C10H18INO2. In a article£¬once mentioned of 301673-14-3

PHENYLDIFLUOROMETHYL-SUBSTITUTED PROLINAMIDE COMPOUND

[Problem] To provide a compound useful as a cathepsin S inhibitor. [Means for Solution] The present inventors have examined a compound that has a cathepsin S inhibitory effect and is usable as an active ingredient of a pharmaceutical composition for preventing and/or treating autoimmune disease including systemic lupus erythematosus (SLE) and lupus nephritis, allergies, or graft rejection of an organ, bone marrow or tissue, and have found that a phenyldifluoromethyl-substituted prolinamide compound of the present invention has the cathepsin S inhibitory effect, thereby completing the present invention. The phenyldifluoromethyl-substituted prolinamide compound of the present invention has the cathepsin S inhibitory effect and is useful as an agent for preventing and/or treating autoimmune disease including SLE and nephritis, allergies, or graft rejection of an organ, bone marrow or tissue.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H23499N – PubChem