Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 10310-21-1, Name is 2-Amino-6-chloropurine, SMILES is NC1=NC(Cl)=C2NC=NC2=N1, belongs to piperidines compound. In a document, author is Kasturi, Siva Prasad, introduce the new discover, COA of Formula: C5H4ClN5.
Synthesis, molecular modeling and evaluation of alpha-glucosidase inhibition activity of 3,4-dihydroxy piperidines
Biological evaluation of 3,4-dihydroxy piperidines as alpha-glucosidase inhibitors is being reported for the first time. Forty-five derivatives (amides, di-amides and sulfonamides) were made using cis and trans 3,4-dihydroxy piperidines to evaluate their alpha-glucosidase inhibition activity. Polar groups (-OH, -NH2) on phenyl ring having derivatives 5i, 5l, 7g, 7i & 12j showed excellent activity compared to standard references. Acarbose, Voglibose and Miglitol were used as standard references. Molecular docking simulations were done for compounds to identify important binding modes responsible for inhibition activity of alpha-glucosidase. (C) 2018 Elsevier Masson SAS. All rights reserved.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 10310-21-1 is helpful to your research. COA of Formula: C5H4ClN5.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem