In an article, author is Tanaka, Nao, once mentioned the application of 143900-44-1, Name is (S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate, molecular formula is C10H19NO3, molecular weight is 201.26, MDL number is MFCD04115307, category is piperidines. Now introduce a scientific discovery about this category, COA of Formula: C10H19NO3.
Can Heteroarenes/Arenes Be Hydrogenated Over Catalytic Pd/C Under Ambient Conditions?
Hydrogenation of over a dozen aromatic compounds, including both heteroarenes and arenes, over palladium on carbon (Pd/C, 1-100 mol%) with H-2-balloon pressure at room temperature is reported. Analyses using pyridine as a model substrate revealed that acetic acid was the best solvent, as using only 1 mol% Pd/C provided piperidine quantitatively. Substrate scope analysis and density functional theory calculations indicated that reaction rates are highly dependent on frontier molecular orbital characteristics and the steric bulkiness of substituents. Moreover, the established method was used for the concise synthesis of the anti-Alzheimer drug donepezil (Aricept (R)).
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 143900-44-1, COA of Formula: C10H19NO3.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem