Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 13925-07-0, Name is 2-Ethyl-3,5-dimethylpyrazine, molecular formula is , belongs to piperidines compound. In a document, author is Dawood, Rafid S., Recommanded Product: 13925-07-0.
Synthesis, identification and molecular docking studies ofN-functionalized piperidine derivatives linked to 1,2,3-triazole ring
New derivatives of piperidine bearing a 1,2,3-triazole ring designed and synthesized smoothly over six steps fromN-protected piperidone-4-one. These steps included reduction of the carbonyl group/tosylation of the resulting alcohol providing tosyl derivative in a good yield, followed by nucleophilic substitution and Cu-catalysed azide-alkyne cycloaddition. By removing the protecting group and functionalizing amine groupviareductive amination gave the desired design in moderate to very good yields. Molecular modeling studies of these compounds predicted possible binding modes into the active site of dopamine receptor D2.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 13925-07-0, in my other articles. Recommanded Product: 13925-07-0.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem