86542-94-1, 1-(Piperidin-4-yl)propan-1-one is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
86542-94-1, General procedure: HOBt*H2O (969 mg, 7.17 mmol), EDCI*HCl(1.37 g, 7.17 mmol), 2,2,6,6-tetramethylpiperidin-4-amine (2.49 mL,3.00 mmol) and Et3N (3.31 mL, 13.9 mmol) were added to a solution of 2-(benzo[d][1,3]dioxol-5-ylamino)-2-oxoacetic acid (1.00 g, 4.78 mmol) in DMF(23.9 mL) at 0 C. The reaction mixture was heated to room temperature and stirred for 20 h. Subsequently, the reaction mixture was concentrated under reduced pressure. Saturated aqueous NaHCO3 was added to the residue, andthe mixture was extracted with CHCl3 (150 mL 3), then washed with brineand dried over MgSO4. Concentration under reduced pressure followed by column chromatography (MeOH/CHCl3, 1/10) provided the title compound 5 (1.46 g, 88% yield) as white powder.
86542-94-1 1-(Piperidin-4-yl)propan-1-one 18620952, apiperidines compound, is more and more widely used in various fields.
Reference：
Article; Mizuguchi, Takaaki; Harada, Shigeyoshi; Miura, Tomoyuki; Ohashi, Nami; Narumi, Tetsuo; Mori, Hiromi; Irahara, Yu; Yamada, Yuko; Nomura, Wataru; Matsushita, Shuzo; Yoshimura, Kazuhisa; Tamamura, Hirokazu; Bioorganic and Medicinal Chemistry Letters; vol. 26; 2; (2016); p. 397 – 400;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem