With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.79098-75-2,3-Piperidin-4-yl-3,4-dihydro-1H-quinazolin-2-one,as a common compound, the synthetic route is as follows.,79098-75-2
EXAMPLE 12 1-[3,5-dibromo-N-[[4-[3,4-dihydro-2(1H)-oxoquinazolin-3-yl]-1-piperidinyl]cyanoiminomethyl]-D-tyrosyl]-4-(4-methyl-1-piperazinyl)piperidine Prepared analogously to Example 7 from N-cyanoiminodiphenylcarbonate, 3,4-dihydro-3-(4-piperidinyl)-2(1H)-quinazolinone and 1-[3,5-dibromo-D-tyrosyl]-4-(4-methyl-1-piperazinyl)-piperidine in a yield of 13% of theory. Colorless, amorphous substance. IR (KBr): 1674 (C=O), 2173 (CN) cm-1 Rf: 0.30 (eluant dichloromethane/methanol/conc. ammonia 8/2/0.2 v/v/v) ESI-MS: (M+H)+=784/786/788 (Br2)
As the paragraph descriping shows that 79098-75-2 is playing an increasingly important role.
Reference£º
Patent; Boehringer Ingelheim Pharma KG; US6313097; (2001); B1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem