14813-01-5, 1-Benzylpiperidin-3-ol is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
14813-01-5, To a mixture of 0.50 g (2.62 mmol) of rac-2 and 1 ml of dry pyridine 0.57 ml (3.50 mmol) of butanoic anhydride was added at 0 C under nitrogen. The resulting mixture was stirred over night at room temperature. The reaction mixture was diluted with dichloromethane and then extracted with a saturated sodium carbonate solution (2 x 4 ml) and with 4 ml of a saturated sodium chloride solution. The organic phase was dried with sodium sulfate and then concentrated at reduced pressure to give 0.65 g (2.49 mmol) of rac-5 as a pale yellow oil (95% yield). 1H NMR (300 MHz,CDCl3, d ppm): 0.98 (t, 3H, J = 5.9 Hz); 1.43-1.45 (m, 1H); 1.63-1.90 (m, 3H); 2.31-2.40 (m, 4H); 2.46 (m, 2H), 2.67-2.83 (m,2H); 3.58-3.64 (m, 2H); 4.85-4.89 (m, 1H); 7.22-7.31 (m, 5H); TLC Rf = 0.60.
14813-01-5 1-Benzylpiperidin-3-ol 85773, apiperidines compound, is more and more widely used in various fields.
Reference：
Article; Tofani, Giorgio; Petri, Antonella; Piccolo, Oreste; Tetrahedron Asymmetry; vol. 26; 12-13; (2015); p. 638 – 643;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem