Downstream Synthetic Route Of 1,4-Dioxa-8-azaspiro[4.5]decane

Welcome to talk about 177-11-7, If you have any questions, you can contact Ma, XS; Han, YX; Bennett, DJ or send Email.. Category: piperidines

An article Selective Synthesis of 1-Dialkylamino-2-alkylbicyclo-[1.1.1]pentanes WOS:000592988800072 published article about TRANSFORMATIONS; PHOTOCONVERSION; PHOTOCHEMISTRY; REACTIVITY; PHOTOLYSIS in [Ma, Xiaoshen; Han, Yongxin; Bennett, David J.] Merck & Co Inc, Dept Discovery Chem, Boston, MA 02115 USA in 2020, Cited 44. The Name is 1,4-Dioxa-8-azaspiro[4.5]decane. Through research, I have a further understanding and discovery of 177-11-7. Category: piperidines

Compared to the abundance of methodologies accessing 1-substituted and 1,3-disubstuted bicyclo[1.1.1] pentanes (BCPs), the synthetic accessibility of BCPs with substitutions at the methylene position has been limited. Herein, we report a selective synthesis of 1-dialkylamino-2-alkylbicyclo[1.1.1]pentanes from prefunctionalized starting materials. We also achieved further functionalizations of these 1,2-disubstituted BCPs and developed a synthesis of these compounds with minimum necessity of chromatographic purifications starting from 1,3-dichloroacetone. Finally, we also detailed the synthesis of a 1,2,3-trisubstituted BCP analogue.

Welcome to talk about 177-11-7, If you have any questions, you can contact Ma, XS; Han, YX; Bennett, DJ or send Email.. Category: piperidines

Reference:
Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem