With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.10338-57-5,4-(Piperidin-1-yl)benzaldehyde,as a common compound, the synthetic route is as follows.,10338-57-5
A solution of the compound m2 (0.3323 g, 1 mmol) and 4-piperidin-1-yl-benzaldehyde (0.2081 g, 1.1 mmol) was added to a rear wall pressure vessel followed by 2 mL of DMSO, 10 mL of trimethylchlorosilane, C for 48 h. After TLC monitoring reaction, the crude product was purified by silica gel column chromatography (eluent: V (ethyl acetate): V (methanol): V (ammonia) = 10: 1: 0.1) To give a pale yellow solid, 0.4281 g, 85% yield.
The synthetic route of 10338-57-5 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Sun Yat-Sen University; HUANG, ZHISHU; TAN, JIAHENG; WANG, YUQING; (41 pag.)CN106220631; (2016); A;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem