1032903-63-1, tert-Butyl 4-(4-amino-5-isopropoxy-2-methylphenyl)piperidine-1-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Intermediate 6 (1.0 equiv.) was added to a solution of trisubstituted aniline 49 (5.0 g) in 100 mL CH3CN at room temperature. The resulting reaction mixture was heated to 80C and stirred for 8 h. After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The mixture was stirred at 0C for 2 h and filtered. The crude product 7 was used in the next step without further purification. A small sample of 7 was recrystallised to give a brown solid, m.p. 220-221C (CH3CN/MTBE); 1H NMR delta 11.3 (s, 1H), 9.21 (s, 1H), 8.01 (m, 3H), 7.87 (m, 1H), 7.65 (m, 1H), 7.45 (m,1H), 6.73 (s, 1H), 4,59 (m, 1H), 4.28 (m, 2H), 3.27 (m, 1H), 2,79 (m,3H), 2.07 (s, 1H), 1.93 (m, 2H). 1.41-1.75 (m, 25H); 13C NMR delta 154.9,136.5, 134.2, 131.4, 125.8, 79.6, 71.7, 55.0, 38.4, 32.5, 28.5, 22.2, 18.8,15.4; HRMS (m/z) [M+Na]+ calcd for C33H44N6O7SNa 691.2890, found 691.2885., 1032903-63-1
1032903-63-1 tert-Butyl 4-(4-amino-5-isopropoxy-2-methylphenyl)piperidine-1-carboxylate 59764580, apiperidines compound, is more and more widely used in various fields.
Reference£º
Article; Liu, Haidong; Li, Yuan; Wang, Dongdong; Qin, Yu; Ji, Min; Journal of Chemical Research; vol. 39; 8; (2015); p. 475 – 477;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem