Discovery of (S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate

Synthetic Route of 143900-44-1, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 143900-44-1.

Synthetic Route of 143900-44-1, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 143900-44-1, Name is (S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate, SMILES is O=C(N1C[C@@H](O)CCC1)OC(C)(C)C, belongs to piperidines compound. In a article, author is Vereshchagin, Anatoly N., introduce new discover of the category.

Stereoselective one-pot synthesis of polycyanosubstituted piperidines

An effective and facile multicomponent method for the synthesis of polysubstituted piperidines is described. The Michael-Mannich type cascade of benzylidenemalononitriles with aromatic aldehydes and ammonium acetate or aqueous ammonia provides convenient access to the stereoselective synthesis of 3,3,5,5-tetracyano-2,4,6-triarylpiperidines in good to excellent yields in one-pot manner. Ammonium acetate or aqueous ammonia plays a role both as a catalyst and as a nitrogen source. It is established that the reaction proceeds via sequence of equilibriums and a competitive mechanisms are implemented. [GRAPHICS] .

Synthetic Route of 143900-44-1, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 143900-44-1.

Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem