Formula: C7H13NO2. I found the field of Chemistry very interesting. Saw the article Preparation of Chiral Allenes through Pd-Catalyzed Intermolecular Hydroamination of Conjugated Enynes: Enantioselective Synthesis Enabled by Catalyst Design published in 2019, Reprint Addresses Malcolmson, SJ (corresponding author), Duke Univ, Dept Chem, Durham, NC 27708 USA.. The CAS is 177-11-7. Through research, I have a further understanding and discovery of 1,4-Dioxa-8-azaspiro[4.5]decane.
In this study, we establish that conjugated enynes undergo selective 1,4-hydroamination under Pd catalysis to deliver chiral allenes with pendant allylic amines. Several primary and secondary aliphatic and aryl-substituted amines couple with a wide range of mono- and disubstituted enynes in a nonenantioselective reaction where DPEphos serves as the ligand for Pd. Benzophenone imine acts as an ammonia surrogate to afford primary amines in a two-step/one-pot process. Examination of chiral catalysts revealed a high degree of reversibility in the C-N bond formation that negatively impacted enantioselectivity. Consequently, an electron-poor ferrocenyl-PHOX ligand was developed to enable efficient and enantioselective enyne hydroamination.
About 1,4-Dioxa-8-azaspiro[4.5]decane, If you have any questions, you can contact Adamson, NJ; Jeddi, H; Malcolmson, SJ or concate me.. Formula: C7H13NO2
Reference：
Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem