Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Recommanded Product: 2-Amino-6-chloropurine, 10310-21-1, Name is 2-Amino-6-chloropurine, molecular formula is C5H4ClN5, belongs to piperidines compound. In a document, author is Bandaru, Siva Sankar Murthy, introduce the new discover.
Pd/PTABS: Catalyst for Room Temperature Amination of Heteroarenes
A mild and highly efficient catalytic amination procedure for chloroheteroarenes at ambient temperature using the Pd/PTABS catalytic system is reported. The protocol is selective for the amination of chloroheteroarenes using secondary amines such as piperidine, pyrrolidine, and several others. The exceptional mildness of the developed protocol is beneficial for the synthesis of a crucial Buparlisib intermediate as well as the formal synthesis of Alogliptin in competitive yields.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 10310-21-1. Recommanded Product: 2-Amino-6-chloropurine.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem