Synthesis and evaluation of photophysical and electrochemical properties of vinyl chalcogenide derivatives of phenothiazines was written by Dilelio, Marina Cardoso;Kaufman, Teodoro S.;Iglesias, Bernardo Almeida;Silveira, Claudio C.. And the article was included in Dyes and Pigments in 2022.Application of 50-52-2 This article mentions the following:
The Wittig-Horner mediated syntheses of phenothiazines carrying vinylsulfide and vinylselenide motifs attached to the aromatic ring(s) or connected to the central nitrogen atom of the heterocycle, and the subsequent study of their photophys. and electrochem. properties, are reported. These compounds were obtained as mixtures of geometric isomers, in good to excellent yields. To complete the study, a small set of vinylsulfoxide and vinylsulfone derivatives was also prepared from the corresponding oxidized phosphinoxides. The photophys. properties of the compounds were examined in solvents of varying polarity, in which they presented absorption maxima in the UV region, with molar absorptivity coefficients compatible with symmetry-allowed 蟺-蟺* electronic transitions. The heterocyclic derivatives were fluorescent. Compounds bearing vinylsulfide moieties associated to the nitrogen atom of the heterocycle displayed less intense fluorescence than the phenothiazine derivatives carrying vinylchalcogenides bonded to the aromatic ring; the latter also exhibited more red-shifted absorption spectra, and Stokes shifts in the range 6115-8170 cm-1 with weak dependence of solvent polarity. The sulfoxide and sulfones displayed more red-shifted spectra than the corresponding sulfides. The cyclic voltammograms of all derivatives exhibited a common pattern of reversible or quasi-reversible processes in the anodic region, related to the phenothiazine unit. In the experiment, the researchers used many compounds, for example, 10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine (cas: 50-52-2Application of 50-52-2).
10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine (cas: 50-52-2) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Piperidine derivatives are being utilized in different ways as anticancer, antiviral, antimalarial, antimicrobial, antifungal, antihypertension, analgesic, anti-inflammatory, anti-Alzheimer, antipsychotic and/or anticoagulant agents.Application of 50-52-2
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem