Screening of pharmaceuticals in coastal waters of the southern coast of Viti Levu in Fiji, South Pacific was written by Dehm, Jasha;Singh, Shubha;Ferreira, Marta;Piovano, Susanna;Fick, Jerker. And the article was included in Chemosphere in 2021.Synthetic Route of C32H39NO4 The following contents are mentioned in the article:
The global reliance on pharmaceuticals coupled with the lack of effective treatment methods has resulted in pseudo-persistence of pharmaceuticals within the environment. Globally, efforts to quantify and monitor pharmaceuticals within the environment have been well underway, however few studies have been made within small Pacific Islands. This study aims at screening for the occurrence and concentration of pharmaceutical residues within the southern coastal waters of Fiji’s main island, Viti Levu. Water samples were collected from a depth of ca. 0.6 m from seven sites and were analyzed for 80 pharmaceuticals via a combination of chromatog. and heated electrospray ionization. Seventy-two pharmaceuticals were quantified at least once with average concentrations ranging between 0.04 ng/L (diltiazem) and 19 ng/L (ketoconazole), and with all but two pharmaceuticals (trimethoprim and biperiden) being present in less than 50% of the samples. Findings suggest that even though the release of pharmaceuticals into the marine environment is sporadic and pharmaceuticals are diluted via turbulent mixing, there are measurable concentrations of pharmaceuticals in Fiji and these pollutants are not necessarily restricted to highly populated areas. This study involved multiple reactions and reactants, such as 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid (cas: 83799-24-0Synthetic Route of C32H39NO4).
2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid (cas: 83799-24-0) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Piperidine derivatives bearing a masked aldehyde function in the 蔚-position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Synthetic Route of C32H39NO4
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem