Chenard, B. L. et al. published their research in Bioorganic & Medicinal Chemistry Letters in 1993 | CAS: 119431-25-3

Oxindole N-methyl-D-aspartate (NMDA) antagonists was written by Chenard, B. L.;Butler, T. W.;Shalaby, I. A.;Prochniak, M. A.;Koe, B. K.;Fox, C. B.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 1993.Recommanded Product: 1-(4-Chlorophenyl)-2-(4-(4-fluorobenzyl)piperidin-1-yl)ethan-1-ol This article mentions the following:

Replacement of the phenol group in the noncompetitive NMDA antagonist ifenprodil with oxindole results in a new series of nontraditional NMDA antagonists. Thus, (hydroxypiperdinylethyl)oxindoles I were prepared by Friedel-Crafts acylation of oxindole II with MeCHClCOCl, nucleophilic substitution with 4-benzylpiperidine, and reduction with NaBH₄ in EtOH. In combination with threo relative stereochem., improved NMDA antagonist potency and selectivity may be achieved. In the experiment, the researchers used many compounds, for example, 1-(4-Chlorophenyl)-2-(4-(4-fluorobenzyl)piperidin-1-yl)ethan-1-ol (cas: 119431-25-3Recommanded Product: 1-(4-Chlorophenyl)-2-(4-(4-fluorobenzyl)piperidin-1-yl)ethan-1-ol).

1-(4-Chlorophenyl)-2-(4-(4-fluorobenzyl)piperidin-1-yl)ethan-1-ol (cas: 119431-25-3) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Piperidine derivatives bearing a masked aldehyde function in the 蔚-position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Recommanded Product: 1-(4-Chlorophenyl)-2-(4-(4-fluorobenzyl)piperidin-1-yl)ethan-1-ol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem