Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Formula: C5H11NO.
Chen, Zimin;Zheng, Songlin;Wang, Zijie;Liao, Zixuan;Yuan, Weiming research published 《 Electron Donor-Acceptor Complex Enabled Photocyanation of Tertiary Amines with a Stable and User-Friendly Cyanobenziodoxolone Reagent》, the research content is summarized as follows. A visible light-induced photocyanation of tertiary amines e.g., 1-((trimethylsilyl)methyl)piperidine by a stable, less-toxic and user-friendly CN reagent cyanobenziodoxolone (CBX) was developed. This cyanation process does not require any photocatalyst, oxidant, base or additives, and represents a set of extremely mild and succinct reaction conditions and a broad substrate scope. In addition to the frequently used N-aryl amine derivatives e.g, 2-thiomorpholinoacetonitrile, more challenging tertiary aliphatic amines (modified by a α-silyl substituent) can also be photocyanated smoothly. Mechanistic studies reveal that the cyanation reaction is enabled by an electron donor-acceptor (EDA) complex formed by the interaction between the amine and the cyanobenziodoxolone reagent.
5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., Formula: C5H11NO
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem