Chen, Qiumeng’s team published research in Sensors and Actuators, B: Chemical in 305 | CAS: 826-36-8

Sensors and Actuators, B: Chemical published new progress about 826-36-8. 826-36-8 belongs to piperidines, auxiliary class Natural product, name is 2,2,6,6-Tetramethylpiperidin-4-one, and the molecular formula is C9H17NO, Recommanded Product: 2,2,6,6-Tetramethylpiperidin-4-one.

Chen, Qiumeng published the artcileSize-controllable Fe-N/C single-atom nanozyme with exceptional oxidase-like activity for sensitive detection of alkaline phosphatase, Recommanded Product: 2,2,6,6-Tetramethylpiperidin-4-one, the publication is Sensors and Actuators, B: Chemical (2020), 127511, database is CAplus.

Nanozymes become currently a frontier of chem. research. However, exploiting a novel nanozyme with high activity, good stability and reproducibility is challenging. Here, size-controllable Fe-N/C nanozymes containing exclusive single Fe atoms coordinated Fe-Nx sites were succesfully prepared through a facile pyrolysis of size controllable Fe-Zn ZIFs precursors. The Fe-N/C nanozymes exhibit exceptional high oxidase-mimicking activity able to catalyze oxidation of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) by dissolved oxygen to generate blue product. Their catalytic activities can be regulated by modulating the molar ratios of methanol to metal salts (e.g., Fe and Zn) through which the size controllable Fe-Zn ZIFs precursors are obtained. Upon introduction of ascorbic acid (AA) into Fe-N/C/TMB system, complete inhibition of TMB oxidation was observed, resulting in significant decline in absorbance with a clear color change. In the presence of alk. phosphatase (ALP), ascorbic acid 2-phosphate (AAP) is hydrolyzed to produce AA. When coupled with AAP, a novel colorimetric biosensor platform was fabricated for ALP activity screening in the range of 0.05 U/L-100 U/L (four orders of magnitude) with an ultra-low limit of detection of 0.02 U/L. The work provides a promising strategy to rationally design the transition metal-N/C single-atom nanozyme with high oxidase-like activity.

Sensors and Actuators, B: Chemical published new progress about 826-36-8. 826-36-8 belongs to piperidines, auxiliary class Natural product, name is 2,2,6,6-Tetramethylpiperidin-4-one, and the molecular formula is C9H17NO, Recommanded Product: 2,2,6,6-Tetramethylpiperidin-4-one.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem