Category: 948015-72-3

Extracurricular laboratory:new discovery of tert-Butyl 3-(cyanomethyl)piperidine-1-carboxylate

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 948015-72-3, help many people in the next few years.Quality Control of: tert-Butyl 3-(cyanomethyl)piperidine-1-carboxylate

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Quality Control of: tert-Butyl 3-(cyanomethyl)piperidine-1-carboxylate, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 948015-72-3, Name is tert-Butyl 3-(cyanomethyl)piperidine-1-carboxylate, molecular formula is C12H20N2O2. In a Patent, authors is £¬once mentioned of 948015-72-3

FUSED BICYCLIC COMPOUND FOR INHIBITING ACTIVITY OF TYROSINE KINASE

A fused bicyclic compound having an effect in inhibition of the activity of a tyrosine kinase, and preparation and use thereof are disclosed. In particular, a compound of formula (I) or a pharmaceutically acceptable salt, a stereoisomer, a solvate, a hydrate, a polymorph, a prodrug or an isotopic variation thereof, as well as a pharmaceutical composition comprising same are disclosed. As a selective irreversible inhibitor of Bruton’s tyrosine kinase, the described compound can be used for preventing or treating diseases such as inflammation, autoimmune diseases (such as rheumatoid arthritis), xenogeneic immune diseases and cancers.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 948015-72-3, help many people in the next few years.Quality Control of: tert-Butyl 3-(cyanomethyl)piperidine-1-carboxylate

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H17956N – PubChem

 

Simple exploration of 948015-72-3

The synthetic route of 948015-72-3 has been constantly updated, and we look forward to future research findings.

948015-72-3, tert-Butyl 3-(cyanomethyl)piperidine-1-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,948015-72-3

tert-butyl 3-(cyanomethyl)piperidin-1-carboxylate (0.292 g, 1.3 mmol) obtained in Step C was dissolved in 13mL of DCM and cooled to 0C. HCl (1.3 mL, 5.6 mmol, 4 M 1,4-dioxane solution) was slowly added thereto. After stirringat 0C for 1 hour, the reaction solution was concentrated under reduced pressure to obtain the title compound (0.18 g,86 %).1H-NMR (DMSO-d6) delta 9.16 (2H, brs), 3.21 (2H, t), 2.73 (1H, m), 2.61 (3H, m), 2.11 (1H, m), 1.81 (2H, m), 1.69 (1H, m),1.27 (1H, m)

The synthetic route of 948015-72-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; LG Chem, Ltd.; KIM, Young Kwan; PARK, Sang Yun; JOO, Hyun Woo; CHOI, Eun Sil; PAEK, Seung Yup; KANG, Seung Wan; KIM, Byung Gyu; LEE, Chang Seok; KIM, Sung Wook; LEE, Sang Dae; (369 pag.)EP3239143; (2017); A2;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem