With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.915226-44-7,1-N-Boc-3-(R)-Cyanopiperidine,as a common compound, the synthetic route is as follows.,915226-44-7
2(C) (R)-3-(N-Hydroxycarbamimidoyl)-piperidine-1-carboxylic acid tert-butyl ester A solution of (R)-3-cyano-piperidine-1-carboxylic acid tert-butyl ester (457 g, 2.18 mmol) and aqueous hydroxylamine (50% in water, 0.534 mL, 8.72 mmol) in ethanol (10 mL) was refluxed for 2 h. The solvent was evaporated under reduced pressure to afford the title compound that was used for the next step without further purification. Yield: 80%; LCMS (RT): 2.71 min (Method A); MS (ES+) gave m/z: 244.0.
As the paragraph descriping shows that 915226-44-7 is playing an increasingly important role.
Reference：
Patent; NIKEM RESEARCH SRL; ADDEX PHARMA SA; US2009/215822; (2009); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem