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Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Safety of (R)-tert-Butyl (piperidin-3-ylmethyl)carbamate, Which mentioned a new discovery about 879275-33-9

A series of chiral lactam carboxamides of aminomethylpiperidine were synthesized and investigated for the collagen induced in vitro anti-platelet efficacy and collagen plus epinephrine induced in vivo pulmonary thromboembolism. The compound 31a (30 muM/kg) displayed a remarkable antithrombotic efficacy (60% protection) which was sustained for more than 24 h and points to its excellent bioavailability. The compounds 31a (IC50 = 6.6 muM) and 32a (IC50 = 37 muM), as well as their racemic mixture 28i (IC50 = 16 muM) significantly inhibited collagen-induced human platelet aggregation in vitro. Compound 34c displayed dual mechanism of action against both collagen (IC50 = 3.3 muM) and U46619 (IC50 = 2.7 muM) induced platelet aggregation. The pharmacokinetic study of 31a indicated very faster absorption, prolonged and constant systemic exposure and thereby exhibiting better therapeutic response.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H16740N – PubChem

 

Can You Really Do Chemisty Experiments About (R)-tert-Butyl (piperidin-3-ylmethyl)carbamate

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Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 879275-33-9, molcular formula is C11H22N2O2, introducing its new discovery. Application In Synthesis of (R)-tert-Butyl (piperidin-3-ylmethyl)carbamate

The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H16735N – PubChem