Category: 877399-73-0

Chemistry is an experimental science, HPLC of Formula: C13H20IN3O2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 877399-73-0, Name is 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine

The present invention relates to a structurally novel [1,2,4]triazolo[4,3-b][1,2,4]triazine compounds represented by formula (I) or formula (II), pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates or solvates thereof, and also relates to a preparation method of the compounds, a pharmaceutical composition comprising a therapeutically effective amount of the compounds, as well as the use thereof as protein tyrosine kinase inhibitors, particularly as c-Met inhibitors, in the preparation of medicaments for the prevention and/or treatment of diseases associated with c-Met abnormality.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. HPLC of Formula: C13H20IN3O2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 877399-73-0, in my other articles.

Reference：
Piperidine – Wikipedia,
Piperidine | C5H23851N – PubChem

877399-73-0, 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

877399-73-0, The compoundTert-Butyl 4- (4-iodo-1H-pyrazol-1- yl) nicardine- 1 -carboxylate (1.00 g, 2.650 mmol)Dissolved in DMSO (llmL)Then, bis (pinacolato) diboron (942.5 mg, 3.710 mmol)And CH3C00K (1.04 g, 10.60 mmol),After pumping gas (N2) three times,Pd (PPh3) 2Cl2 (93.0 mg, 0.130 mmol) was added.After the reaction was stirred at 80 C for 2 hours,The mixture was cooled to room temperature and filtered off with suction. The filtrate was washed with brine (100 mL ¡Á 3), dried over anhydrous Na 2 SO 4 and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (PE / EtOAc (v / v) = 5/1) The title compound was obtained as a white solid (878.6 mg, 87.9%).

The synthetic route of 877399-73-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; (88 pag.)CN104119331; (2018); B;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem