Category: 873924-08-4

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Safety of tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 873924-08-4, Name is tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate, molecular formula is C15H25NO3. In a Patent, authors is ，once mentioned of 873924-08-4

The present invention relates to substituted benzimidazoles, benzothiazoles and benzoxazoles, processes for their preparation, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H21661N – PubChem

 

Electric Literature of 873924-08-4, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 873924-08-4, Name is tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate,introducing its new discovery.

Type 2 diabetes mellitus (T2DM) is an ever increasing worldwide epidemic, and the identification of safe and effective insulin sensitizers, absent of weight gain, has been a long-standing goal of diabetes research. G-protein coupled receptor 120 (GPR120) has recently emerged as a potential therapeutic target for treating T2DM. Natural occurring, and more recently, synthetic agonists have been associated with insulin sensitizing, anti-inflammatory, and fat metabolism effects. Herein we describe the design, synthesis, and evaluation of a novel spirocyclic GPR120 agonist series, which culminated in the discovery of potent and selective agonist 14. Furthermore, compound 14 was evaluated in vivo and demonstrated acute glucose lowering in an oral glucose tolerance test (oGTT), as well as improvements in homeostatic measurement assessment of insulin resistance (HOMA-IR; a surrogate marker for insulin sensitization) and an increase in glucose infusion rate (GIR) during a hyperinsulinemic euglycemic clamp in diet-induced obese (DIO) mice.

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Piperidine | C5H21657N – PubChem

 

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The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof useful in preventing, treating or lessening the severity of a JAK-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of JAK-mediated disease.

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Piperidine – Wikipedia,
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Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Recommanded Product: 873924-08-4, Which mentioned a new discovery about 873924-08-4

This invention relates to novel 3-aza-spiro[5.5]undec-8-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Recommanded Product: 873924-08-4, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 873924-08-4

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Piperidine – Wikipedia,
Piperidine | C5H21659N – PubChem

 

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, COA of Formula: C15H25NO3, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 873924-08-4, Name is tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate, molecular formula is C15H25NO3. In a Patent, authors is ，once mentioned of 873924-08-4

Fused, tricyclic pyrazolo{1,5-a]pyrimidine compounds of formula A or of formula B: and pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by certain Raf kinases.

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Piperidine – Wikipedia,
Piperidine | C5H21683N – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 873924-08-4. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 873924-08-4

The invention discloses a spiro aryl phosphorus oxide or sulfide as ALK inhibitors, specifically disclosed as inhibitors of ALK of formula (I) below or a pharmaceutically acceptable salt thereof. (by machine translation)

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Piperidine – Wikipedia,
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Described herein are compounds of formula (I) (Formula (I)). The compounds of formula (I) act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity

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Piperidine – Wikipedia,
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Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 873924-08-4, molcular formula is C15H25NO3, introducing its new discovery. Formula: C15H25NO3

The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Formula: C15H25NO3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 873924-08-4

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Piperidine – Wikipedia,
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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Computed Properties of C15H25NO3, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 873924-08-4, Name is tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate, molecular formula is C15H25NO3. In a Patent, authors is £¬once mentioned of 873924-08-4

SUBSTITUTED SPIROAMIDE COMPOUNDS

Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R)

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Piperidine – Wikipedia,
Piperidine | C5H21677N – PubChem

 

873924-08-4, tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,873924-08-4

9-Benzo[b]thiophen-2-yl-3-aza-spiro[5.5]undec-8-eneWas prepared according to method A with the following variation: n-BuLi (1.6 M in hexanes (4 ml_, 6.4 mmol)) was added drop-wise to a solution of benzothiophene (778 mg, 5.80 ml_) in diethyl ether (10 ml_). The reaction was warmed to reflux for 1 h and then cooled to -780C. 9-Oxo-3-aza-spiro[5.5]undecane-3-carboxylic acid terf-butyl ester (500 mg, 1.87 mmol) in diethyl ether was added drop-wise and the mixture was stirred at -780C for 2 h. Mp. 107.3-110.2C.

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Reference£º
Patent; NeuroSearch A/S; WO2007/464; (2007); A1;,
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