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The present invention relates to metallo-beta-lactamase inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-beta-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more beta-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Recommanded Product: 871115-32-1, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 871115-32-1
Reference:
Piperidine – Wikipedia,
Piperidine | C5H18606N – PubChem