Category: 84163-13-3

Related Products of 84163-13-3, In heterogeneous catalysis, the catalyst is in a different phase from the reactants. At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 84163-13-3, name is 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride. In an article，Which mentioned a new discovery about 84163-13-3

A compound of formula (1) is useful as a pharmaceutical and as an intermediate in making paliperidone. wherein Y is an acid-sensitive group of the formula: in which X represents an oxygen atom, a sulfur atom, or an ?NH? group; Z represents a C2-C7 alkylene bridge; and R represents hydrogen or a C1-C4 alkyl group.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.84163-13-3. In my other articles, you can also check out more blogs about 84163-13-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21079N – PubChem

Synthetic Route of 84163-13-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 84163-13-3, Name is 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride, molecular formula is C12H14ClFN2O. In a Patent，once mentioned of 84163-13-3

The present invention is concerned with novel compounds having the formula STR1 the pharmaceutically acceptable acid addition salts thereof and the stereochemically isomeric forms thereof, wherein Alk represents C1-4 alkanediyl; D is a bicyclic heterocycle of formula STR2 wherein each R1 independently is C2-6 alkenyl; C2-6 alkynyl; C3-6 cycloalkyl optionally substituted with C1-4 alkyl; C1-19 alkyl optionally substituted with C3-6 cycloalkyl, halo, C1-6 alkyloxy or cyano; and each R2 independently is hydrogen or C1-4 alkyl. Novel compounds; compositions; processes for preparing novel compounds and intermediates are described.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Synthetic Route of 84163-13-3, you can also check out more blogs about84163-13-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21015N – PubChem

Application of 84163-13-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.84163-13-3, Name is 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride, molecular formula is C12H14ClFN2O. In a Patent，once mentioned of 84163-13-3

The present invention relates to the field of pharmaceutical chemistry, and in particular, to a benzopyrone derivative and a use thereof. The benzopyrone derivative is compound having a structure of formula (I) or a pharmaceutically acceptable salt thereof. It has been found by experiments that, this type of compounds is useful in prevention or treatment of neuropsychical diseases.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 84163-13-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H20990N – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Quality Control of: 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride, Which mentioned a new discovery about 84163-13-3

A new class of phosphoramidate derivatives of 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazole were synthesized in good to excellent yields (78?96%) by an in situ, three-step process. All the synthesized molecules were evaluated for anti-bacterial and anti-fungal activities using in vitro and in silico methods. The results revealed that the compounds 4b, 4d, 4h, 4i, and 4j exhibited the most promising anti-bacterial activity against S. aureus, B. subtilis, K. pneumoniae, S. typhi and P. mirabilis and anti-fungal activity against A. niger and A. flavus when compared with the standard drugs Norfloxacin and Nystatin at concentrations of 25, 50, 75 and 100 mug/mL. The rest of the title compounds have shown moderate activity against all the bacterial and fungal strains. Molecular docking studies revealed that the synthesized compounds have exhibited significant binding modes with high dock scores ranging from ?7.2 to ?9.5 against 3V2B protein when compared with the standard drugs Norfloxacin (?5.8) and Nystatin (?6.6) respectively. Hence, it is suggested that the synthesized phosphoramidate derivatives of 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazole will stand as the promising antimicrobial drug candidates in future.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 84163-13-3, help many people in the next few years.Quality Control of: 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21073N – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Formula: C12H14ClFN2O, Which mentioned a new discovery about 84163-13-3

Process for the purification of paliperidone by formation of a salt thereof, such as the hydrochloride.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 84163-13-3, help many people in the next few years.Formula: C12H14ClFN2O

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21045N – PubChem

Reference of 84163-13-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 84163-13-3, Name is 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride, molecular formula is C12H14ClFN2O. In a Review，once mentioned of 84163-13-3

Isoxazole is an azole with an oxygen atom next to the nitrogen. Isoxazole rings are found in some natural products, such as ibotenic acid and also found in a number of drugs, including COX-2 inhibitor valdecoxib. Furoxan, a nitric oxide donor is containing isoxazolyl group and found in many beta-lactamase resistant antibiotics, such as cloxacillin, dicloxacillin and flucloxacillin. The synthetic androgenic steroid danazol also has an isoxazole ring. The substituted isoxazoles are well developed in literature to possess significant biological activities. The disubstituted and trisubstituted isoxazoles have been reported to exhibit broad range of biological activities such as antimicrobial activity, analgesic activity, anti-inflammatory activity, antioxidant activity, anticancer activity, CNS (central nervous system) activity, antitubercular activity and miscellaneous activities like GABA (gamma-amino butyric acid) agonistic activity, inhibitory activity, antihypertensive activity, and glutamate transporter activity. The present review summarizes up to date information of various biological activities of isoxazole analogs.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Reference of 84163-13-3, you can also check out more blogs about84163-13-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21055N – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Product Details of 84163-13-3, Which mentioned a new discovery about 84163-13-3

The present invention relates to stable polymorphic form of paliperidone and process for its preparation. The chemical name of Paliperidone (I) is 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Formula (I): Paliperidone is useful as anti-psychotic agent in the treatment of psychotic disorders. Paliperidone is available in market under brand name INVEGA.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 84163-13-3, help many people in the next few years.Product Details of 84163-13-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H20991N – PubChem

Related Products of 84163-13-3, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 84163-13-3, Name is 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride,introducing its new discovery.

The invention discloses a 2,6-diketone-piperazine (piperidine) type derivative and an application thereof. The derivative can be applied to preparation of medicines for preventing or treating central nervous system diseases. Animal experiment results show that the derivative has smaller ED50 and stronger action in MK-801-induced high activity and apomorphine-induced climbing animal models as well as has larger ED50 and larger therapeutic indexes in an animal catalepsy model. The derivative is a compound or salt thereof with a general formula (I).

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H21034N – PubChem

Electric Literature of 84163-13-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.84163-13-3, Name is 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride, molecular formula is C12H14ClFN2O. In a Patent，once mentioned of 84163-13-3

A method for preparation of iloperidone is provided which comprises reacting 6-fluoro-3-(4-piperidinyl)-1,2-benzoisoxazole hydrochloride with 1-[4-(3-chloropropoxyl)-3-methoxyphenyl]ethyl ketone in an inorganic alkaline aqueous solution. A crystallization method of iloperidone is also provided which comprises adding seed crystal to the iloperidone solution in ethyl acetate, and then iloperidone crystal is obtained with high purity by controlling the temperature and the stirring speed.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Electric Literature of 84163-13-3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 84163-13-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21075N – PubChem

Application of 84163-13-3, In heterogeneous catalysis, the catalyst is in a different phase from the reactants. At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 84163-13-3, name is 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride. In an article，Which mentioned a new discovery about 84163-13-3

Protein glycation is believed to play an important role in the development of long-term disorders associated with diabetic complications. In view of the wide occurrence of advanced glycation end products (AGE’s) and the oxidative stress derived from them in a variety of diabetic complications, it would be of great interest to identify and develop AGE inhibitors. In this study, synthesis and in vitro antiglycation activity of a small library of forty urea/thiourea derivatives of Phe/Tyr/Glu/Lys-benzisoxazole hybrids are reported. Structures of the compounds were confirmed by IR, NMR, mass spectrometry, and elemental analysis. Most of the title compounds exhibited promising activity. Best antiglycation activity was found for Tyr analogue with methoxy group as a substituent particularly at the para position with IC50 value of 1.9 muM against the positive control, Rutin, with IC50 = 41.9 muM. Thus, the title compounds represent novel class of potent antiglycating agents.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.84163-13-3. In my other articles, you can also check out more blogs about 84163-13-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21043N – PubChem