Category: 78619-84-8

Zauhar, Joseph et al. published their research in Synthesis in 1995 | CAS: 78619-84-8

4,4′-Bipiperidine dihydrochloride (cas: 78619-84-8) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Piperidine derivatives are being utilized in different ways as anticancer, antiviral, antimalarial, antimicrobial, antifungal, antihypertension, analgesic, anti-inflammatory, anti-Alzheimer, antipsychotic and/or anticoagulant agents.Safety of 4,4′-Bipiperidine dihydrochloride

Synthesis of dicyanomethyl and nitro substituted p-polyphenyls and their salts was written by Zauhar, Joseph;Bandrauk, Andre D.;Truong, Kim D.;Michel, Andre. And the article was included in Synthesis in 1995.Safety of 4,4′-Bipiperidine dihydrochloride This article mentions the following:

A one-step, medium-scale synthesis of several novel dicyanomethyl and nitro substituted p-polyphenyls from 4,4′- or 4”-diiodo-p-polyphenyls and from 4-iodo-4′- or 4”-nitro-p-polyphenyls, resp., and sodium malononitrile using a palladium catalyst is reported. A number of organic cation salts of these extended 蟺-electron systems are likewise described. In the experiment, the researchers used many compounds, for example, 4,4′-Bipiperidine dihydrochloride (cas: 78619-84-8Safety of 4,4′-Bipiperidine dihydrochloride).

4,4′-Bipiperidine dihydrochloride (cas: 78619-84-8) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Piperidine derivatives are being utilized in different ways as anticancer, antiviral, antimalarial, antimicrobial, antifungal, antihypertension, analgesic, anti-inflammatory, anti-Alzheimer, antipsychotic and/or anticoagulant agents.Safety of 4,4′-Bipiperidine dihydrochloride

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Patzschke, Christin et al. published their research in Microporous and Mesoporous Materials in 2016 | CAS: 78619-84-8

4,4′-Bipiperidine dihydrochloride (cas: 78619-84-8) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Recommanded Product: 4,4′-Bipiperidine dihydrochloride

An adsorption study on STA-16(Co) was written by Patzschke, Christin;Marshall, Marc;Chaffee, Alan L.. And the article was included in Microporous and Mesoporous Materials in 2016.Recommanded Product: 4,4′-Bipiperidine dihydrochloride This article mentions the following:

Adsorption is considered a promising method for carbon capture. CO2 adsorbents take a variety of forms, but one approach is the use of metal-organic frameworks (MOFs). In this study, the potential of STA-16(Co) to selectively adsorb and sep. CO2 is considered. Isotherms for CO2 and N2 were measured from 0 to 25 bar at temperatures between 25 and 105 掳C to evaluate the potential application in high pressure separation processes. Low pressure CO2 pseudo-isotherms were measured from 0 to 0.5 bar at temperatures between 25 and 105 掳C, together with dry and wet cycling experiments, to determine the applicability of STA-16(Co) in a vacuum swing adsorption (VSA) process. The presence of 1% H2O vapor during ten cycle experiments resulted in a decrease in CO2 working capacity obtained under dry cyclic conditions of 鈭?6% due to the high H2O uptake. In contrast to the majority of MOFs, STA-16(Co) exhibited a good H2O stability and maintained its CO2 adsorption capacity after adsorption/desorption of H2O vapor at 30 and 60% RH at 25 掳C. However the treatment at 90% RH resulted in a small decrease in CO2 adsorption capacity, apparently due to the formation of a different crystal structure. In the experiment, the researchers used many compounds, for example, 4,4′-Bipiperidine dihydrochloride (cas: 78619-84-8Recommanded Product: 4,4′-Bipiperidine dihydrochloride).

4,4′-Bipiperidine dihydrochloride (cas: 78619-84-8) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Recommanded Product: 4,4′-Bipiperidine dihydrochloride

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Extracurricular laboratory:new discovery of 78619-84-8

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Application of 78619-84-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.78619-84-8, Name is 4,4′-Bipiperidine dihydrochloride, molecular formula is C10H22Cl2N2. In a Patent，once mentioned of 78619-84-8

This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands has a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H19978N – PubChem

 

Brief introduction of 78619-84-8

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 78619-84-8, and how the biochemistry of the body works.Electric Literature of 78619-84-8

Electric Literature of 78619-84-8, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.78619-84-8, Name is 4,4′-Bipiperidine dihydrochloride, molecular formula is C10H22Cl2N2. In a article，once mentioned of 78619-84-8

Heteroarylpiperazine and heteroarylbipiperidine derivatives, bearing a 4-piperidine ring instead of an alkylamino side chain to give the semi-rigidity, were prepared and evaluated for their abilities to displace [3H] 8-OH-DPAT binding to the rat hippocampal synaptic membranes. These compounds showed low to moderate affinities for 5-HT1A receptor, with Ki values ranging from 6912 nM to 232 nM. Of these compounds, 8 b and 15 e exhibited the best affinities for 5-HT1A receptor with Ki values of 232 nM and 338 nM, respectively.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 78619-84-8, and how the biochemistry of the body works.Electric Literature of 78619-84-8

Reference：
Piperidine – Wikipedia,
Piperidine | C5H19999N – PubChem

 

Simple exploration of 78619-84-8

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Computed Properties of C10H22Cl2N2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 78619-84-8, in my other articles.

Chemistry is an experimental science, Computed Properties of C10H22Cl2N2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 78619-84-8, Name is 4,4′-Bipiperidine dihydrochloride

Quinolonecarboxylic acid derivatives and their use

A composition comprises a 1,7-disubstituted-4-oxo-3-quinolinecarboxylic acid or 1,7-disubstituted-4-oxo-3-naphthyridinecarboxylic acid derivative which is useful as a prophylactic and/or therapeutic agent for peripheral arterial obstruction, acute myocardial infarction, an antitumor agent, and as a prophylactic and/or therapeutic agent for osteoporosis.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Computed Properties of C10H22Cl2N2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 78619-84-8, in my other articles.

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H20010N – PubChem

 

Simple exploration of 4,4′-Bipiperidine dihydrochloride

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 78619-84-8, help many people in the next few years.SDS of cas: 78619-84-8

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ SDS of cas: 78619-84-8, Which mentioned a new discovery about 78619-84-8

Bicyclic fibrinogen antagonists

This invention relates to compounds of the formulae: whereinA1 is O, S, N?R1 or CHR1;A4 is N?R4 or CHR4;R2 is a sidechain containing an acid or ester group;R1, R4 and R5 are substituents such as H, alkyl and aryl alkyl, andR6 is a sidechain containing a nitrogen group; andpharmaceutically acceptable salts thereof,which are effective for inhibiting platelet aggregation, pharmaceutical compositions for effecting such activity, and a method for inhibiting platelet aggregation.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H19979N – PubChem

 

Brief introduction of 78619-84-8

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Application of 78619-84-8, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 78619-84-8

Application of 78619-84-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.78619-84-8, Name is 4,4′-Bipiperidine dihydrochloride, molecular formula is C10H22Cl2N2. In a Article£¬once mentioned of 78619-84-8

[35S]GTPgammaS binding studies of amphiphilic drugs-activated Gi proteins: A caveat

This paper documents a serious problem met during the testing of Gi protein-activating properties of a new series of synthetic compounds by measuring the induced binding of [35S]GTPgammaS to different subtypes of Gi protein. The problem arose from the strong affinity between [35S]GTPgammaS and the tested compounds, that are characterized by several (2-4) positive charges and high lipophilicity. Apparently, such affinity yields insoluble, labelled complexes that, also in the absence of Gi protein, are retained on the filters and give rise to false positive results.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H19977N – PubChem