New explortion of Methyl piperidine-4-carboxylate hydrochloride

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, name: Methyl piperidine-4-carboxylate hydrochloride, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 7462-86-4, Name is Methyl piperidine-4-carboxylate hydrochloride, molecular formula is C7H14ClNO2. In a Patent, authors is ,once mentioned of 7462-86-4

This invention relates to compounds of the formula: STR1 which are effective for inhibiting platelet aggregation, pharmaceutical compositions for effecting such activity, and a method for inhibiting platelet aggregation.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H10900N – PubChem

 

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The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 7462-86-4 is helpful to your research. Safety of Methyl piperidine-4-carboxylate hydrochloride

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 7462-86-4, name is Methyl piperidine-4-carboxylate hydrochloride, introducing its new discovery. Safety of Methyl piperidine-4-carboxylate hydrochloride

Tartronic acid acetalic ethers and esters of the general formula: STR1 are provided and are useful in treatment of bone dysmetabolism. As examples, Ra and Rb may be hydrogen, B is a C2 -C12 acyl group, R is phenyl and n is 0-12.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H10912N – PubChem

 

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Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: Methyl piperidine-4-carboxylate hydrochloride. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 7462-86-4

Modification of the carboxyl group at the 3-position and introduction of protective groups to the hydroxy group of the 4,1-benzoxazepine derivative 2 (metabolite of 1) were carried out, and the inhibitory activity for squalene synthase and cholesterol synthesis in the liver was investigated. Among these compounds, the glycine derivative 3a and beta-alanine derivative 3f exhibited the most potent inhibition of squalene synthase prepared from HepG2 cells (IC50 = 15 nM). On the other hand, the piperidine-4-acetic acid derivative 4a, which was prepared by acetylation of 3j, was the most effective inhibitor of cholesterol synthesis in rat liver (ED50 = 2.9 mg/kg, po). After oral administration, 4a was absorbed and rapidly hydrolyzed to deacylated 3j. Compound 3j was detected mainly in the liver, but the plasma level of 3j was found to be low. Compounds 3j and 4a were found to be competitive inhibitors with respect to farnesyl pyrophosphate. Further evaluation of 4a as a cholesterol-lowering and antiatherosclerotic agent is underway.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H10918N – PubChem

 

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Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.HPLC of Formula: C7H14ClNO2, you can also check out more blogs about7462-86-4

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A series of sub stituted pyrrolo [2,1-f] [ 1,2,4]triazine and imidazo [2,1 -f] – [ 1,2,4]triazine derivatives, and fused pyridazine analogues there of, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions (Formula (I))

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H10925N – PubChem

 

Top Picks: new discover of Methyl piperidine-4-carboxylate hydrochloride

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Computed Properties of C7H14ClNO2, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 7462-86-4

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ Computed Properties of C7H14ClNO2, Which mentioned a new discovery about 7462-86-4

1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants

The present invention relates to 1,4-disubstituted-piperidinyl compounds and their use as analgesic agents and as muscle relaxants.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H10902N – PubChem

 

Downstream synthetic route of 7462-86-4

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With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7462-86-4,Methyl piperidine-4-carboxylate hydrochloride,as a common compound, the synthetic route is as follows.

7462-86-4, EXAMPLE II The purpose of this example is to demonstrate one method for the preparation of a piperidinyl intermediate of Formula III. To a stirred, room temperature, mixture of isonipecotic acid methyl ester hydrochloride (5.00 g, 2.78*10-2 mole), potassium carbonate (7.70 g, 5.57*10-2 mole), and DMF (100 ml) was added 1-(2-bromoethyl)-4-methoxybenzene (5.99 g, 2.78*10-2 mole). The reaction was then immersed in an oil bath which had been preheated to ca. 90 C. The reaction was heated at ca. 90 C. for ca. 17 hours and was then poured into a separatory funnel containing water and a 2:1 mixture of ethyl acetate:toluene. The two phases were mixed and the aqueous layer was separated. The organic layer was washed two times with H20 and once with saturated aqueous NaCl before being dried over anhydrous Na2 SO4. The drying agent was removed by filtration and the filtrate was evaporated at reduced pressure leaving an oil. Purification by flash chromatography (ethyl acetate) and crystallization from cyclohexane gave 1-[2-(4-methoxyphenyl)ethyl]-4-piperidinecarboxylic acid, methyl ester as a colorless solid: 3.98 g (52%), m.p. 66-68 C. Analysis Calculated for C16 H23 NO3: C, 69.29; H, 8.36, N, 5.05. Found: C, 69.50; H, 8.40; N, 4.94.

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Reference£º
Patent; Merrell Dow Pharmaceuticals Inc.; US4908372; (1990); A;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem