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Related Products of 6789-94-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.6789-94-2, Name is 1-Ethylpiperidin-3-amine, molecular formula is C7H16N2. In a Patent,once mentioned of 6789-94-2

[Problem] A compound which can be used as a pharmaceutical, particularly a insulin secretion promoter or a agent for preventing/treating disease in which GPR40 is concerned such as diabetes or the like, is provided. [Means for resolution] It was found that an oxadiazolidinedione compound which is characterized by the possession of a benzyl or the like substituent binding to the cyclic group via a linker at the 2-position of the oxadiazolidinedione ring, or a pharmaceutically acceptable salt thereof, has excellent GPR40 agonist action. In addition, since the oxadiazolidinedione compound of the present invention showed excellent insulin secretion promoting action and blood glucose level-lowering action, it is useful as an insulin secretion promoter or an agent for preventing/treating diabetes.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H4053N – PubChem

 

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Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 1-Ethylpiperidin-3-amine. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 6789-94-2

The pharmacological activity of several new sulpiride analogues was studied by means of a new approach, based on a potentiometric technique with a pCO2 sensor, capable of detecting carbonic anhydrase inhibition at equilibrium conditions.This procedure gives results stated as percent of inhibition of enzymatic activity (IP, inhibitory power).To prove the reliability of the proposed approach and to study structure-activity relationships, several new molecules were synthesized and tested in comparison with the two sulpiride enantiomers.A possible inhibition mechanism is discussed in terms of experimental evidence obtained from the interactions between the molecular structures of the new synthesized compounds and carbonic anhydrase.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H4014N – PubChem

 

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Reference of 6789-94-2, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.6789-94-2, Name is 1-Ethylpiperidin-3-amine, molecular formula is C7H16N2. In a article,once mentioned of 6789-94-2

Novel quinazoline and cinnoline derivatives having the formula STR1 (wherein one of A and B is CH and the other one of A and B is N; X1 is halogen or CF3 and X3 is one of the groups II, III, IV or V STR2 where Q is lower alkylene; R1 is hydrogen or lower alkyl; R2 and R3 are independently lower alkyl or R2 and R3 are a divalent radical such that HNR2 R3 is a secondary cyclic amine with 5 to 7 ring atoms; R4 is lower alkyl; n is 0 or 1; the rings shown in formulae III and IV are piperidine or pyrrolidine optionally substituted by lower alkyl; and the ring shown in formula V is piperazine optionally substituted by lower alkyl) and their pharmaceutically acceptable salts are useful as pharmaceuticals particularly as anti-hypertensives. Novel intermediates are also described including the corresponding sulphonic acids of formula I (where A, B and X1 are defined above and X3 is OH).

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H4030N – PubChem

 

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To improve upon the activity and properties of the 3-aryl-7-chloro-3,4-dihydro-1,9(2H,10H)-acridinediones, a variety of 1-<(alkylamino)alkylene>imino derivatives (3) were prepared and shown to be highly active antimalarial agents in both rodents and primates.Among structural modifications prepared, including N10-alkyl and C2-substituted analogs, removal of the C9 oxygen, and introduction of an imino side chain at C9, the imines of the N10-H acridinediones were the most active compounds obtained.The <3-(N,N-dimethylamino)propyl>imino derivative of7-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione (9aa) proved to be highly active in advanced studies in primates.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H4011N – PubChem

 

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A novel polyprenyl compound such as a polyprenyl carboxylic acid amide is disclosed. It has antithrombic and antiplatelet aggregation activity.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H4050N – PubChem

 

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SYNTHESIS OF PIPERIDINE DERIVATIVES AS POTENTIAL ANALGETIC AGENTS

Reaction of N-(1-(2-phenylethyl)-4-piperidinyl)propionanilide (I) with phosphorus pentasulfide gave the thioamide VI.Acylation of N-(1-(2-phenylethyl)-4-piperidinyl)aniline with 2-(methoxy)acetic and 2-(methylthio)acetic anhydrides afforded the amides II and III.Treatment of 4-anilino-1-benzylpiperidine-4-methanol with thionyl chloride gave the spirocyclic sulfurous acid ester amide XIV.Reduction of the hydrochloride of ethyl 3-(1-ethoxycarbonyl-4-phenylimino-3-piperidinyl)propionate (XXII) with sodium cyanoborohydride gave the perhydro-1,6-naphthyridine derivative XIX, a model compound in the synthesis of the cyclic analogue of fentanyl (I).Ethyl 4-anilino-1-(2-phenylethyl)-1,2,3,6-tetrahydropyridine-3-carboxylate (XXIX) hydrochloride, obtained by reaction of ethyl 4-oxo-1-(2-phenylethyl)piperidine-3-carboxylate hydrochloride with aniline, was reduced with lithium aluminium hydride to 4-anilino-1-(2-phenylethyl)piperidine-3-methanol (XXXI). 1-Methyl- and 1-benzyl-4-piperidone were reacted with 4-cyclopropylphenylmagnesium bromide and the tertiary alcohols XXXVII and XXXVIII obtained were acylated with propionyl chloride to give the esters XXXIX and XL.The piperidine derivatives XLI, XLVI and XLVIII were prepared as potential neurotropic agents.Alkylation of 8-hydroxy-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine (XLIX) with 2-(2-chloroethyl)-1,3-dioxane and -1,3-dioxolane resulted in the 6,7-benzomorphan derivatives L and LI.Out of the compounds prepared, only the closest fentanyl analogues II, III, and VI showed very strong analgetic activity.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H4023N – PubChem