Category: 55695-51-7

Electric Literature of 55695-51-7, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 55695-51-7, Name is (4-Chlorophenyl)(piperidin-4-yl)methanone hydrochloride, molecular formula is C12H15Cl2NO. In a Patent，once mentioned of 55695-51-7

The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof in which m, n, W, X, Y, Z, R, R1, R2, R3 and R4 are as defined in the specification, for use in therapy.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Electric Literature of 55695-51-7, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 55695-51-7, in my other articles.

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21301N – PubChem

 

Application of 55695-51-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.55695-51-7, Name is (4-Chlorophenyl)(piperidin-4-yl)methanone hydrochloride, molecular formula is C12H15Cl2NO. In a Patent，once mentioned of 55695-51-7

The invention provides a compound having the formula (I): or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR5; J1-J2 is N=C(R6), (R7)C=N, (R8)N-C(O), (R8)2C-C(O), N=N or (R7)C=C(R6); A is an optionally substituted saturated C1-7 hydrocarbon linker group having a maximum chain length of 5 atoms extending between R1 and NR2R3 and a maximum chain length of 4 atoms extending between E and NR2R3, one of the carbon atoms in the linker group being optionally replaced by oxygen or nitrogen; E is a monocyclic or bicyclic carbocyclic or heterocyclic group or an acyclic group X-G wherein X is CH2, O, S or NH and G is a C1-4 alkylene chain wherein one of the carbon atoms is optionally replaced by O, S or NH; R1 is hydrogen or an aryl or heteroaryl group; R2 and R3 are each hydrogen, optionally substituted C1-4 hydrocarbyl or optionally substituted C1-4 acyl; or NR2R3 forms an imidazole group or a saturated monocyclic heterocyclic group having 4-7 ring members; or NR2R3 and A together form a saturated monocyclic heterocyclic group having 4-7 ring members which is optionally substituted by C1-4 alkyl; or NR2R3 and the adjacent carbon atom of linker group A together form a cyano group; or R1, A and NR2R3 together form a cyano group; and R4, R5, R6, R7 and R8 are each independently selected from hydrogen and various substituents as defined in the claims, wherein the compound is for use in: (a) the treatment or prophylaxis of a disease or condition in which the modulation (e.g. inhibition) of ROCK kinase or protein kinase p70S6K is indicated; and/or (b) the treatment of a subject or patient population in which the modulation (e.g. inhibition) of ROCK kinase or protein kinase p70S6K is indicated.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 55695-51-7 is helpful to your research. Application of 55695-51-7

Reference：
Piperidine – Wikipedia,
Piperidine | C5H21307N – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 55695-51-7. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 55695-51-7

COMPOUNDS

The invention provides compounds of general formula (I) wherein: R 1 represents optionally substituted, C 1 -C 12 alkyl or optionally substituted 3- to 10-membered saturated or unsaturated ring system comprising up to two ring carbon atoms that form carbonyl groups and comprising up to 4 ring heteroatoms independently selected from nitrogen, oxygen and sulfur; m is 0-1; Q represents OCH 2 , C 1 -C 4 alkylene or C 2 -C 4 alkenylene; T represents C(O)NH, or when m is 0, T may additionally represent a bond or NH, or when m is 1 and Q represents C 1 -C 4 alkylene, T may additionally represent NH; n is 1-4; each R 2 and R 3 independently represents H or C 1 -C 4 alkyl; V represents N, and W represents N or CH; X represents O, C(O), CH(OH), SO 2 , NH or N(C 1 -C 6 alkyl), provided that when W represents N, then X represents either C(O) or SO 2 and when W represents CH, then X is other than SO 2 ; R 4 represents optionally substituted phenyl; R 5 and R 6 each independently represent H, C 1 -C 6 alkyl or hydroxyC 1 -C 6 alkyl, or R 5 and R 6 together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocyclic ring; R 7 and R 8 each independently represent H or C 1 -C 6 alkyl; and R 9 represents OH or ?NR 7 R 8 ; processes for their preparation, pharmaceutical compositions containing them and their use in therapy

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 55695-51-7, you can also check out more blogs about55695-51-7

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H21305N – PubChem