Category: 5472-49-1

Electric Literature of 5472-49-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.5472-49-1, Name is 1-(3-Chloropropyl)piperidine hydrochloride, molecular formula is C8H17Cl2N. In a Patent£¬once mentioned of 5472-49-1

Histamine H3-receptor ligands and their therapeutic application

The present patent application concerns new compounds of formula (I) with R 1 and R 2 taken together with the nitrogen atom to which they are attached, form a saturated nitrogen-containing ring, A is a saturated C1-4 alkylene and B a C3-4 alkylene or alkenylene chain; their preparation and their use as a H3 receptor ligand for treating e.g. CNS disorders like Alzheimer’s disease.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 5472-49-1

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H13180N – PubChem

 

Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 5472-49-1, molcular formula is C8H17Cl2N, introducing its new discovery. name: 1-(3-Chloropropyl)piperidine hydrochloride

The unambiguous synthesis and NMR assignment of 4-alkoxy and 3-alkylquinazolines

Contrary to a number of reports, alkylations of the privileged 3,4-dihydroquinazoline scaffold provide N3-alkylated products, and not 4-alkoxyquinazolines. To correctly assign the structure, 13C NMR shifts of the -Z-CHn- (Z=O, N) fragment are necessary; resonances in the 45-55 ppm range are indicative of N3-alkylation. Treatment of 3,4-dihydroquinazoline-4-one with p-TsCl afforded the N3-tosylated compound, whose reaction with an amine yielded the corresponding N3-alkyl derivative. A mechanism corroborated by 15N-labeling involving pyrimidine ring opening and recyclisation is proposed. Finally, the unambiguous preparation of 4-alkoxyquinazolines is described via treatment of 3,4-dihydroquinazoline-4-ones with PCl5 followed by an alkoxide.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, name: 1-(3-Chloropropyl)piperidine hydrochloride, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 5472-49-1

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H13258N – PubChem