Category: 53617-35-9

Synthetic Route of 53617-35-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53617-35-9, Name is 4-Morpholinopiperidine, molecular formula is C9H18N2O. In a Patent，once mentioned of 53617-35-9

The present invention relates to compounds of formula (I), (formula I) wherein: X is C(=0) or S(0)2; R1 is selected from the group consisting of N-linked piperazinyl, relinked piperidine, and N-linked diazabicyclo[3.2.1]octane, wherein R1 is optionally substituted with one or more groups; R2 and R3 are each independently selected from H, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, and C3-8cycloalkyl, wherein any C1-6alkyl, C2-6alkenyl, C2-6alkynyl, and C3-8cycloalkyl is optionally substituted with one or more groups; or R2 and R3 taken together with the carbon to which they are attached form a 3-, 4-, 5-, or 6-membered carbocyclic ring that is optionally substituted with one or more groups; R4 and R5 are each independently selected from H, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, and C3-8cycloalkyl, wherein any C1-6alkyl, C2-6alkenyl, C2-6alkynyl, and C3-8cycloalkyl is optionally substituted with one or more groups; or R4 and R5 taken together with the carbon to which they are attached form a 3-, 4-, 5-, or 6-membered carbocyclic ring that is optionally substituted with one or more groups; and R6 is a 5-10 membered heteroaryl, 5-10 membered heterocycle, or a 6-10 membered aryl, which 5-10 membered heteroaryl, 5-10 membered heterocycle, and 6-10 membered aryl is optionally substituted with one or more groups; useful as inhibitors of one or more histone demethylses, such as KDM2b. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 53617-35-9

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9676N – PubChem

Related Products of 53617-35-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53617-35-9, Name is 4-Morpholinopiperidine, molecular formula is C9H18N2O. In a Patent，once mentioned of 53617-35-9

The invention relates to substituted N-aryl heterocycles and to the physiologically tolerated salts and physiologically functional derivatives thereof.Compounds of the formula I 1 in which the radicals have the stated meanings, the N-oxides and the physiologically tolerated salts thereof and process for the preparation thereof are described. The compounds are suitable for example as anorectic agents.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Related Products of 53617-35-9, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 53617-35-9

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9708N – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， category: piperidines, Which mentioned a new discovery about 53617-35-9

New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition and also serve as leads for designing future new drugs. This annual review covers the synthesis of thirty-seven NCEs that were approved for the first time in 2014 and one drug which was approved in 2013 and was not covered in a previous edition of this review.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 53617-35-9, help many people in the next few years.category: piperidines

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9755N – PubChem

Related Products of 53617-35-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53617-35-9, Name is 4-Morpholinopiperidine, molecular formula is C9H18N2O. In a Patent，once mentioned of 53617-35-9

The present invention relates to certain compounds (e.g., imidazopyrazine, imidazopyridine, imidazopyridazine and imidazpyrimidine compounds) that act as inhibitors of the MAP kinase interacting kinases MNK2a, MNK2b, MNK1a, and MNK1b. The present invention further relates to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the preparation of a medicament for the prophylaxis and treatment of diseases (e.g., proliferative diseases (e.g., cancer), inflammatory diseases, Alzheimer’s disease), as well as methods of treating these diseases.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Related Products of 53617-35-9, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 53617-35-9

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9679N – PubChem

Chemistry is an experimental science, Recommanded Product: 4-Morpholinopiperidine, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 53617-35-9, Name is 4-Morpholinopiperidine

2,7-Disubstituted oxazolo[5,4-f]quinoxalines were synthesized from 6-amino-2-chloroquinoxaline in four steps (iodination at C5, substitution of the chloro group, amidation and copper-catalysed cyclization) affording 28 to 44% overall yields. 2,8-Disubstituted oxazolo[5,4-f]quinoxaline was similarly obtained from 6-amino-3-chloroquinoxaline (39% overall yield). For the synthesis of other oxazolo[5,4-f]quinoxalines, amidation was rather performed before substitution; moreover, time-consuming purification steps were avoided between the amines and the final products (38 to 54% overall yields). Finally, a more efficient method involving merging of the last two steps in a sequential process was developed to access more derivatives (37 to 65% overall yields). Most of the oxazolo[5,4-f]quinoxalines were evaluated for their activity on a panel of protein kinases, and a few 2,8-disubstituted derivatives proved to inhibit GSK3 kinase. While experiments showed an ATP-competitive inhibition on GSK3beta, structure-activity relationships allowed us to identify 2-(3-pyridyl)-8-(thiomorpholino)oxazolo[5,4-f]quinoxaline as the most potent inhibitor with an IC50 value of about 5 nM on GSK3alpha.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: 4-Morpholinopiperidine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 53617-35-9, in my other articles.

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9802N – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 53617-35-9, name is 4-Morpholinopiperidine, introducing its new discovery. Product Details of 53617-35-9

The present invention encompasses compounds of general formula (I) wherein the groups R2 to R4, A, X and m are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain compounds of this kind and their use as medicaments.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 53617-35-9 is helpful to your research. Product Details of 53617-35-9

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9700N – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， COA of Formula: C9H18N2O, Which mentioned a new discovery about 53617-35-9

New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition and also serve as leads for designing future new drugs. This annual review covers the synthesis of thirty-seven NCEs that were approved for the first time in 2014 and one drug which was approved in 2013 and was not covered in a previous edition of this review.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, COA of Formula: C9H18N2O, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 53617-35-9

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9756N – PubChem

Chemistry is an experimental science, SDS of cas: 53617-35-9, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 53617-35-9, Name is 4-Morpholinopiperidine

The invention relates to a method for preparing pharmaceutical intermediates, in particular to a 4? Morpholino process for preparation of piperidines. The invention will create 1? Benzyltin? 4? Piperidone and morpholine reaction is carried out by preparing 4? (1? Benzyl piperidine? 4? Yl) morpholine b hydrochloric acid, then to continue reaction produce the final product is 4? Morpholino piperidine. Creation method of this invention is simple and convenient, high yield and purity of the product, mild reaction conditions the safety is high, is particularly suitable for industrial production. (by machine translation)

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. SDS of cas: 53617-35-9, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 53617-35-9, in my other articles.

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9711N – PubChem

Reference of 53617-35-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53617-35-9, Name is 4-Morpholinopiperidine, molecular formula is C9H18N2O. In a Patent，once mentioned of 53617-35-9

The present invention relates to a compound of the formula wherein R1 is substituted aryl, heteroaryl and the like, R2 and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X’ is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 53617-35-9

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9687N – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 53617-35-9, name is 4-Morpholinopiperidine, introducing its new discovery. name: 4-Morpholinopiperidine

Novel diaminothiazoles of formula (I): [image] are discussed. These compounds selectively inhibit the activity of Cdk4 and are thus useful in the treatment or control of cancer, in particular, the treatment or control of solid tumors. This invention also provides pharmaceutical compositions containing such compounds and methods of treating or controlling cancer, most particularly, the treatment or control of breast, lung, colon, and prostate tumors.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 53617-35-9 is helpful to your research. name: 4-Morpholinopiperidine

Reference：
Piperidine – Wikipedia,
Piperidine | C5H9752N – PubChem