Category: 4972-31-0

Proietti, Giampiero published the artcileAccessing Perfluoroaryl Sulfonimidamides and Sulfoximines via Photogenerated Perfluoroaryl Nitrenes: Synthesis and Application as a Chiral Auxiliary, HPLC of Formula: 4972-31-0, the publication is Journal of Organic Chemistry (2021), 86(23), 17119-17128, database is CAplus and MEDLINE.

A light-promoted generation of perfluorinated aromatic nitrenes, from perfluorinated azides, that subsequently were allowed to react with sulfinamides and sulfoxides, generating achiral and chiral sulfonimidamides (SIAs) and sulfoximines (SOIs). One of enantiopure SIAs was evaluated as a novel chiral auxiliary in Grignard additions to imines yielding product in up to 96:4 diastereomeric ratio.

Journal of Organic Chemistry published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C11H15NOS, HPLC of Formula: 4972-31-0.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem

Boehme, Horst published the artcileAminal splittings with sulfonic, sulfinic, and sulfenic acid halides, Recommanded Product: 1-(Phenylsulfinyl)piperidine, the publication is Chemiker-Zeitung (1978), 102(2), 64-5, database is CAplus.

RSO_nCl (R = Ph, Me, CCl₃; n = 0-2) reacted with (R¹R²N)₂CH₂ (NR¹R² = NMe₂, piperidino, 4-methylpiperazino, NMeCH₂Ph) to give 53-94% R¹R²N⁺:CH₂Cl^– and RSO_nNR¹R².

Chemiker-Zeitung published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C11H15NOS, Recommanded Product: 1-(Phenylsulfinyl)piperidine.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem

Sardar, Mohammed Y. R. published the artcileSynthesis of Lewis^X-O-Core-1 threonine: A building block for O-linked Lewis^X glycopeptides, Name: 1-(Phenylsulfinyl)piperidine, the publication is Carbohydrate Research (2017), 47-53, database is CAplus and MEDLINE.

Lewis^X (Le^X) is a branched trisaccharide Galβ1â†?(Fucα1â†?)GlcNAc that is expressed on many cell surface glycoproteins and plays critical roles in innate and adaptive immune responses. However, efficient synthesis of glycopeptides bearing Le^X remains a major limitation for structure-function studies of the Le^X determinant. Here we report a total synthesis of a Le^X pentasaccharide 1 (I) using a regioselective 1-benzenesulfinylpiperidine/triflic anhydride promoted [3 + 2] glycosylation. The presence of an Fmoc-threonine amino acid facilitates incorporation of the pentasaccharide in solid phase peptide synthesis, providing a route to diverse O-linked Le^X glycopeptides. The described approach is broadly applicable to the synthesis of a variety of complex glycopeptides containing O-linked Le^X or sialyl Lewis^X (sLe^X).

Carbohydrate Research published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C11H15NOS, Name: 1-(Phenylsulfinyl)piperidine.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem

Wimmer, Alexander published the artcileN-Arylation of NH-Sulfoximines via Dual Nickel Photocatalysis, HPLC of Formula: 4972-31-0, the publication is Organic Letters (2019), 21(8), 2740-2744, database is CAplus and MEDLINE.

The pharmaceutically underexplored sulfoximine moiety has emerged as a potentially active pharmaceutical ingredient. We developed a scalable synthetic route to N-arylated sulfoximines from the resp. “free” NH-sulfoximines and bromoarenes. Our strategy is based on a dual nickel photocatalytic approach, is applicable for a broad scope of substrates, and exhibits a highly functional group tolerance. In addition, we could demonstrate that other sulfoximidoyl derivatives like sulfonimidamides and sulfinamides proceed smoothly under the developed reaction conditions.

Organic Letters published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C15H16O3, HPLC of Formula: 4972-31-0.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem

Yamada, Takeshi published the artcileHighly efficient synthesis of oligo-N-acetyl-glucosamines by iterative glycosylation of Di- and tetrachlorophthaloyl-protected thio-glucosamines, Related Products of piperidines, the publication is Chemistry Letters (2005), 34(11), 1556-1557, database is CAplus.

The iterative stereoselective glycosylation of di- and tetrachlorophthaloyl-protected thio-glucosamines, which act as both glycosyl donors and acceptors, gives the corresponding protected oligo-glucosamines. Subsequent removal of the protecting groups followed by acetylation of the free amines affords oligo-N-acetyl-glucosamines in good to excellent combined yields.

Chemistry Letters published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C7H8BBrO3, Related Products of piperidines.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem

v. Braun, Julius published the artcileSuffinic acids, Synthetic Route of 4972-31-0, the publication is Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen (1923), 549-53, database is CAplus.

In an attempt to prepare compounds of the type R₂NCS.S.SO₂R’, that their stability might be compared with compounds of the type R(O:)C.S.C(: S)NH₂, R’SO₂Cl was caused to react with R₂NCSSH.NHR₂; instead of the expected compound however, the corresponding (R₂NSCS-)₂ was obtained, together with R’SO₂H.NHR₂. That is, the sulforyl chloride simply acted as an oxidizing agent, itself being reduced to the sulfinic acid. 4 mols. Me₂NH, 2 mols. CS₂ and 1 mol. PbSO₂2Cl in dry Et₂O gave about 80% of the theory of (Me₂NCS.S-)₂ and PhSO₂H, isolated through the Fe salt. Dipiperidyl-thiuram disulfide (A), C₁₂H₂₀N₇S₄, obtained in 60% yield, m. 128°. Tetralin-β-sulfonylpiperidide, C₁₀H₁₁SO₂NC₅H₁₀, obtained in a small yield (in addition to a 70% yield of A), from the interaction of C₅H₁₁N, CS₂ and C₁₀H₁₁SO₂Cl, m. 98-100°. Tetralin-β-sulfinic acid, needles from concentrated aqueous solution, m. 87-8°. Benzenesulfinic anilide, from the chloride and PhNH₂ in dry Et₂O at 0°, m. 112-4°. Heated with acids, a deep-seated change occurs, without a smooth splitting into the components. The latter takes place by short heating with dilute alc. KOH or upon longer standing in the cold. The piperidide sinters at 8O° and m. 83°. The dimethylamide, yellow oil, b_2-3 90°. The amide, prepared in Et₂O with Et₂O-NH₃, m. 121°. Toluene-p-sulfinic amide, small needles, m. 120°; anilide, m. 138°.

Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C19H15NO3, Synthetic Route of 4972-31-0.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem

Wei, Peng published the artcileFactors Affecting Stereocontrol during Glycosidation of 2,3-Oxazolidinone-Protected 1-Tolylthio-N-acetyl-D-glucosamine, Product Details of C11H15NOS, the publication is Journal of Organic Chemistry (2005), 70(10), 4195-4198, database is CAplus and MEDLINE.

It is demonstrated that a ring-fused 2,3-oxazolidinone-protected derivative of 1-tolylthio-N-acetyl-D-glucosamine, e.g. β-I (R = SPhMe), undergoes high-yield stereoselective glycosidation under mild donor activation conditions to give the corresponding glycosides, e.g. I (R = OBn). Stereoselective formation of α-linked or β-linked glycosides is dependent on reactivity of acceptor alcs., where rate of glycosidation correlates to stereochem. outcome. Evidence for the role of glycosyl triflate intermediates and the N-acetyl substituent of the 2N,3O-oxazolidinone ring in stereochem. control is presented.

Journal of Organic Chemistry published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C8H15NO, Product Details of C11H15NOS.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem