Awesome and Easy Science Experiments about 439811-37-7

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, SDS of cas: 439811-37-7, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 439811-37-7, Name is 1-Boc-4-(4-Bromobenzoyl)piperidine, molecular formula is C17H22BrNO3. In a Patent, authors is £¬once mentioned of 439811-37-7

BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF

The present invention relates to certain compounds (e.g., imidazopyrazine, imidazopyridine, imidazopyridazine and imidazpyrimidine compounds) that act as inhibitors of the MAP kinase interacting kinases MNK2a, MNK2b, MNK1a, and MNK1b. The present invention further relates to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the preparation of a medicament for the prophylaxis and treatment of diseases (e.g., proliferative diseases (e.g., cancer), inflammatory diseases, Alzheimer’s disease), as well as methods of treating these diseases

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 439811-37-7, help many people in the next few years.SDS of cas: 439811-37-7

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H23814N – PubChem

 

Simple exploration of 439811-37-7

439811-37-7 1-Boc-4-(4-Bromobenzoyl)piperidine 22890526, apiperidines compound, is more and more widely used in various.

439811-37-7, 1-Boc-4-(4-Bromobenzoyl)piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a stirred solution of 1 g (3.15 mmol) of compound 5a in 10 mL of THF was added 1.3 mL (3.25 mmol) of n-BuLi at -78 C. After 20 min, a solution of 0.92 g (2.5 mmol) of compound 8 was added and the mixture was warmed to 0 C. over 1 h. It was quenched with 50 mL of H2O and extracted with three 70 mL portions of dichloromethane. The combined organic extracts were washed with 30 mL of brine, and concentrated. The residue was purified by silica gel chromatography eluting with a gradient from 1 to 3% methanol in dichloromethane containing 1% NH4OH to give 1.7 g of compound 9a.

439811-37-7 1-Boc-4-(4-Bromobenzoyl)piperidine 22890526, apiperidines compound, is more and more widely used in various.

Reference£º
Patent; Schering Corporation; US2005/49269; (2005); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem